9月
Werner syndrome RecQ helicase-IN-1；Werner 綜合征 RecQ 解旋酶-IN-1Werner syndrome RecQ helicase-IN-1 (2024/9/12)
簡(jiǎn)介：werner syndrome recq helicase-in-1 is a potent werne r syndrome recq dna deconjugase (wrn) inhibitor that can be used to study cancers such as colon and stomach cancer.
Deoxyfuconojirimycin hydrochloride；化合物 Deoxyfuconojirimycin hydrochlorideDeoxyfuconojirimycin, Hydro (2024/9/12)
簡(jiǎn)介：deoxyfuconojirimycin hydrochloride acts as a specific competitive inhibitor targeting human liver α-l-fucosidase.
AKT Kinase Inhibitor hydrochloride；化合物 AKT Kinase Inhibitor hydrochlorideAKT Kinase Inhibitor hydroc (2024/9/12)
簡(jiǎn)介：akt kinase inhibitor hydrochloride is an akt kinase inhibitor with anti-tumor activity [1] .
β-Aminopropionitrile hydrochloride；化合物 β-Aminopropionitrile hydrochlorideBAPN hydrochloride；BAPN hyd (2024/9/12)
簡(jiǎn)介：β-aminopropionitrile (bapn) hydrochloride is a specific, irreversible, and orally active inhibitor of lysyl oxidase (lox), effectively targeting the active site of lox or loxl isoenzymes.
Glucocorticoid receptor modulator 1；化合物 Glucocorticoid receptor modulator 1Glucocorticoid receptor m (2024/9/12)
簡(jiǎn)介：glucocorticoid receptor modulator 1 is a potent, orally active, non-steroidal selective glucocorticoid receptor modulator, exhibiting ic50 values of 9 nm and 130 nm against nf-κb and ap-1, respectively. it effectively reduces the expression of inflammatory factors such as il-6, il-1β, and tnf-α, and alleviates dermatitis in mice.
Atorvastatin hemicalcium trihydrate化合物 Atorvastatin hemicalcium trihydrate阿托伐他汀半鈣三水合物|||阿托他伐汀半鈣三水合物 (2024/9/12)
簡(jiǎn)介：atorvastatin hemicalcium trihydrate, an orally active hmg-coa reductase inhibitor, effectively reduces blood lipids. it also inhibits human sv-smc proliferation and invasion, showing ic50 values of 0.39 μm and 2.39 μm, respectively.
D-erythro-Sphingosine hydrochloride；化合物 D-erythro-Sphingosine hydrochlorideErythrosphingosine hydroc (2024/9/12)
簡(jiǎn)介：d-erythro-sphingosine hydrochloride, also known as erythrosphingosine, serves as a specific trpm3 activator and induces retinoblastoma protein dephosphorylation.
Guanosine 5’-diphosphate；鳥(niǎo)苷-5ˊ-二磷酸GDP；GDP|||鳥(niǎo)苷-5ˊ-二磷酸 (2024/9/12)
簡(jiǎn)介：guanosine 5´-diphosphate (gdp) as potential iron mobilizer, preventing the hepcidin-ferroportin interaction and modulating the interleukin-6/stat-3 pathway.
Carbomethoxycarbonyl-D-Pro-D-Phe-OBzl；化合物 Carbomethoxycarbonyl-D-Pro-D-Phe-OBzlCarbomethoxycarbonyl- (2024/9/12)
簡(jiǎn)介：carbomethoxycarbonyl-d-pro-d-phe-obzl is an hiv-1 inhibitor that functions by interacting with gp120, thereby preventing its binding to cd4. this mechanism helps to maintain cd4-dependent t cell function.
Eleven-Nineteen-Leukemia Protein IN-3；化合物 Eleven-Nineteen-Leukemia Protein IN-3Eleven-Nineteen-Leuke (2024/9/12)
簡(jiǎn)介：eleven-nineteen-leukemia protein in-3, an orally active enl yeats domain inhibitor, exhibits potent activity with an ic50 of 15.4 nm. it downregulates myc expression via enl in cells and enhances enl protein´s thermal stability in vitro [1].
Eleven-Nineteen-Leukemia Protein IN-2；化合物 Eleven-Nineteen-Leukemia Protein IN-2Eleven-Nineteen-Leuke (2024/9/12)
簡(jiǎn)介：eleven-nineteen-leukemia protein in-2 (compound 23), an enl inhibitor, exhibits an ic50 of 10.7 nm and is utilized for leukemia research [1].
Eleven-Nineteen-Leukemia Protein IN-1；化合物 Eleven-Nineteen-Leukemia Protein IN-1Eleven-Nineteen-Leuke (2024/9/12)
簡(jiǎn)介：eleven-nineteen-leukemia protein in-1 is a potent inhibitor of the enl yeats domain, exhibiting an ic50 of 14.5 nm. it binds to the enl protein, consequently increasing its thermal stability in vitro [1].
Thiamphenicol glycinate hydrochloride化合物 Thiamphenicol glycinate hydrochloride甲砜霉素甘氨酸酯鹽酸鹽 (2024/9/12)
簡(jiǎn)介：thiamphenicol glycinate hydrochloride is a broad-spectrum antibacterial agent utilized in research on respiratory tract infections.
2-Deoxy-D-glucose 6-phosphate disodium；化合物 2-Deoxy-D-glucose 6-phosphate disodium2-Deoxy-D-glucose 6 (2024/9/12)
簡(jiǎn)介：2-deoxy-d-glucose 6-phosphate disodium, a derivative of glucose analog 2-deoxy-d-glucose, is synthesized in mammalian cells through hexokinase activity on 2-dg. it functions as a competitive inhibitor of glucose metabolism, specifically obstructing glycolysis by targeting hexokinase.
ADRA1D receptor antagonist 1 free base；化合物 ADRA1D receptor antagonist 1 free baseADRA1D receptor ant (2024/9/12)
簡(jiǎn)介：adra1d receptor antagonist 1 (free base) antagonist ( k i =1.6 nm). adra1d receptor antagonist 1 (free base) dose-dependently inhibits bladder contraction with an ic 30 value of 15 nm. adra1d receptor antagonist 1 (free base) can be used in studies of overactive bladder disorders such as urinary urgency, frequency and incontinence.
Maropitant馬羅皮坦馬羅匹坦|||馬羅皮坦 (2024/9/12)
簡(jiǎn)介：maropitant is a selective neurokinin (nk1) receptor antagonist.
(R)-BI-2852；化合物 (R)-BI-2852(R)-BI-2852 (2024/9/12)
簡(jiǎn)介：(r)-bi-2852 can be used as (r)-5-isoindolin-1-one is used as an inhibitor of the ras family of proteins and as a compound for the treatment and prevention of tumours. (r)-bi-2852 has antiproliferative and antitumour agent activity.
Octadecyl Rhodamine B chloride；十八基羅丹明B氯化物Octadecyl Rhodamine B chloride (2024/9/12)
簡(jiǎn)介：octadecyl rhodamine b chloride, also known as rboe, is a polarity-sensitive dye that is often used as a chromophore with other compounds to stain cell membranes and has applications in the assembly of organic molecules, in membrane structures and in the transfer of electron energy in the structural domains of proteins.
Compound T72082(SC)；化合物 T72082(SC)Compound T72082(SC) (2024/9/12)
簡(jiǎn)介：ros-in-1 is a mitochondrial ros inhibitor that can be used to reduce oxidative stress or inhibit reactive oxygen species (ros) production.
CpCDPK1/TgCDPK1-IN-2；化合物CpCDPK1/TgCDPK1-IN-2CpCDPK1/TgCDPK1-IN-2 (2024/9/12)
簡(jiǎn)介：cpcdpk1/tgcdpk1-in-2 is a dual inhibitor of cpcdpk1 and tgcdpk1 with ic50 values of 12 and 5 nm for cpcdpk1 and tgcdpk1, respectively.cpcdpk1/tgcdpk1-in-2 can be used in the study of diseases associated with infection of toxoplasmas such as toxoplasma gondii, cryptosporidium parvum and c. hominus. cpcdpk1/tgcdpk1-in-2 can be used to study diseases associated with infections of toxoplasma gondii (t. gondii), cryptosporidium parvum (c. parvum), and cryptosporidium hominus (c. hominus).
AMD 3465 hexahydrobromide；化合物AMD 3465 hexahydrobromideGENZ-644494 (hexahydrobromide)；GENZ-644494 (he (2024/9/12)
簡(jiǎn)介：amd 3465 hexahydrobromide (genz-644494 (hexahydrobromide)) is a cxcr4 receptor antagonist with potential anticancer and anti-hiv activity.
Biotin-aniline；生物素-苯胺Biotin-aniline (2024/9/12)
簡(jiǎn)介：biotin-aniline is a probe that reacts strongly to rna and dna. biotin-aniline is highly efficient and is used to capture subcellular transcriptomes in living cells with high spatial specificity.
Xanthine oxidoreductase-IN-4；黃嘌呤氧化還原酶-IN-4Xanthine oxidoreductase-IN-4 (2024/9/12)
簡(jiǎn)介：xanthine oxidoreductase-in-4 is an orally active xanthine oxidoreductase (xor) inhibitor that inhibits xor with an ic50 value of 29.3 nm.xanthine oxidoreductase-in-4 can be used to study hyperuricemia.
Imidacloprid-urea；化合物 T72077(SC)Imidacloprid-urea (2024/9/12)
簡(jiǎn)介：imidacloprid-urea is a secondary metabolite of imidacloprid. imidacloprid is a potent and widely used neonicotinoid with inhibitory effects on pests of cereals, vegetables, tea and cotton. imidacloprid-urea can occupy or block the adsorption sites of imidacloprid on the soil, which may affect the fate, transport and bioavailability of imidacloprid in the environment.
H2-Gamendazole；化合物H2-GamendazoleH2-Gamendazole (2024/9/12)
簡(jiǎn)介：h2-gamendazole is a novel compound for spermatogenesis inhibition and cancer therapy as an inhibitor of heat shock proteins and/or elongation factor 1 alpha, and is an hsp90 regulator.
HyT36；化合物HyT36HyT36 (2024/9/12)
簡(jiǎn)介：hyt36 is a small molecule hydrophobic tag that selectively destabilizes and promotes the degradation of fusion proteins and the pseudokinase her3. hyt36 can treat cells expressing erht induced acutely.
BTA-EG4 hydrate；BTA-EG4水合物BTA-EG4 hydrate (2024/9/12)
簡(jiǎn)介：bta-eg4 hydrate can be used to diagnose, prevent or reduce the symptoms of amyloid-related diseases like alzheimer´s disease and can be used to improve cognitive function.
AKOS037652256；化合物AKOS037652256AKOS037652256 (2024/9/12)
簡(jiǎn)介：akos037652256 can be used as a trpml modulator for the treatment of diseases associated with trpml activity such as lysosomal accumulation disorders, muscular dystrophy, common age-related neurodegenerative diseases, oxidative stress or reactive oxygen species (ros)-related diseases and ageing.
2-benzylsulfanyl-6-methoxy-4-methylquinazoline；化合物T720722-benzylsulfanyl-6-methoxy-4-methylquinazoli (2024/9/12)
簡(jiǎn)介：2-benzylsulfanyl-6-methoxy-4-methylquinazoline can be used as a trpml modulator for the treatment of diseases associated with trpml activity, such as lysosomal storage disease, muscular dystrophy, oxidative stress or reactive oxygen species (ros)-related diseases and ageing.
WAY-299017；化合物WAY-299017WAY-299017 (2024/9/12)
簡(jiǎn)介：way-299017 is a potent and selective upps inhibitor for the treatment of bacterial infections.
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